ISSN 1662-4009 (online)

ey0018.2-17 | Gestational Diabetes Mellitus: Neonatal and Long-term Consequences | ESPEYB18

2.17. Altered pancreas remodeling following glucose intolerance in pregnancy in mice

SK Szlapinski , AA Botros , S Donegan , RT King , G Retta , BJ Strutt , DJ Hill

J Endocrinol. 2020 May;245(2):315–326. doi: 10.1530/JOE-20-0012. PMID: 32171178.As it is not possible to study the histology of the pancreas post-partum in humans, this study used a mouse model of mild glucose intolerance to assess the changes in pancreatic islets after post-partum and assess the impact of pro-inflammatory cytokines. Mice with glucose intolerance during pregnancy continue...